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to learn about recent ashg activities and to provide suggestions to the Societys leadership. 117 /10:00 Alterations in NFkB signaling contribute to the bone fragility in osteogenesis imperfecta type. Mulvihill, MD, University of Oklahoma Health Sciences Center. Ashg/eshg Building Bridges: Zika: From Virus to Host Response to Vector Control Room 220B, Level 2, Convention Center Moderators : Peter. 60 /11:15 Discovery and prevalence of germline and somatic mutations in patients with advanced renal cell carcinoma in MSK-impact cancer genes. We also show how disrupting critical genes involved in a specific process leads to distinct effects across different subsets of cells in a tissue, and why understanding these discrete effects will lead to a better understanding of normal developmental processes as well as reveal the. 88 /12:15 Zebrafish larvae as a model system for high-throughput, image-based genetic screens in cardiometabolic diseases. Davis, ashg 2017 Program Committee Daniel Doherty, ashg 2017 Program Committee 293 /5:30 The contribution of rare variants, polygenic risk, and novel candidate genes to the hereditary risk of breast cancer in a large cohort of breast cancer families. Introduction: Joann Boughman, looking for sex in Carlsbad University System of Maryland Recipients: Edward.
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Vanderbilt Univ Med Ctr Meharry Med Col, Nashville. 3022 /12:20 A multi-hit de novo mutation model for idiopathic simplex autism. As the human genetics community rapidly moves towards understanding the functional consequences of various changes in our genome, it will be important to study that consequence at the level where the effects are first felt: the individual cell. Polygenic Risk Scores and Genetic Correlation in Complex Disease Room 320, Level 3, Convention Center Moderators : Nilanjan Chatterjee, Johns Hopkins Univ, Baltimore Jennifer Brody, Univ Washington, Seattle 203 /11:00 Polygenic risk scores identify novel relationships between complex traits. Ludwig, Univ Bonn, Germany Brian. 4:45 PM Phenotypic and genomic matchmaking through PhenoDB and GeneMatcher.
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